Laboratories are the New Entrants in Personalized Medicine But Will Become a Dominant Force - Diaceutics

Laboratories are the New Entrants in Personalized Medicine But Will Become a Dominant Force

July 6th, 2012

Maria Fe Paz

Maria Fe Paz of Diaceutics considers that laboratories will become key influencers, ultimately emerging as one of the most dominant stakeholder groups in the future personalized medicine space.

From the melting pot of opportunity that personalized medicine represents, we contend that stakeholders who had less market power under the traditional model of ‘one size fits all’ drugs will be able to grab a more central role in the effective diffusion of personalized medicine. This has already been witnessed by the invigorating growth of molecular diagnostics driven by a diagnostic industry seeking to move beyond a ‘low price, high volume’ business model to claim equal value for—and reward from—its contribution towards better clinical and financial outcomes.

However, we suggest that it will be clinical laboratories and not the diagnostic companies that will ultimately emerge as one of the most dominant stakeholder groups in the future of personalized medicine. Here are some of  the reasons for this bullish view:

  1. Actually, laboratorians have always been among the early innovators in the space. Take, for example, the work of Stanley Cohen, whose career started in 1959 as assistant professor of biochemistry at Vanderbilt University. Dr. Cohen discovered, isolated, purified and sequenced epidermal growth factor (EGF), a protein that stimulates the growth of epithelial and other cells and enhances certain developmental growth cascades. We can expect more discoveries from this quarter as targeted therapies are explored in research institutions across the globe.
  2. Laboratorians already integrate testing into their institutions. Earlier, faster diffusion of testing will ultimately be critical to the success of personalized medicine. Laboratorians hold the keys to these particular jewels and may have an equal or greater influence with physicians than pharma or diagnostic representatives in terms of educating them about new tests.
  3. The personalized medicine testing market may always be served by two technologies, developed kits and lab developed tests. The more complex and multi-technology the testing algorithm, the less the laboratory developed kit will be able to compete. Consequently, pharma companies seeking efficient testing markets may partner with diagnostic companies to help with regulatory needs and the infusion of testing choices for labs, but increasingly we will see them ensure that all patient samples are tested to the highest quality, regardless of the underlying technology.

This topic will be explored in much more depth as part of an article, ‘The Importance Of Early Engagement With Laboratories To Ensure Seamless Availability Of Companion Diagnostics In Parallel With Therapy Launches’, that we anticipate will be published later this year in a special issue of the Journal of Personalized Medicine edited by Felix Frueh, entitled ‘Untold Stories about Personalized Medicine: If You Thought Personalized Medicine Is for Others to Worry About, Think Again.’

Stay tuned . . .


View all blogs

Webinars & Podcasts

August 20th, 2019
Podcast: How Diaceutics is repairing the diagnostic testing ecoystem for patients worldwide
Diaceutics CEO, Peter Keeling joins Pat Kenny on Newstalk FM to discuss how analyzing Big Data to implement better diagnostic testing can help patients access better treatment options for cancer and other life-threatening diseases.
July 5th, 2019
Liquid Biopsy in NSCLC
View all

Expert Insights

April 19th, 2018
The CMS National Coverage Decision on NGS
I. Introduction On March 16, 2018, the Centers for Medicare and Medicaid Services (CMS) finalized a National Coverage Determination (NCD) that cove...
January 19th, 2018
What does the EU IVD Regulation mean for companion diagnostics and LDTs?
Dave Smart, PhD, Director at Diaceutics, discusses the introduction of the EU IVD Regulation. While it is considered a necessary step, the Regulati...
View all expert insights

Competitive Benchmarking Reports

October 21st, 2019
Pharma Precision Medicine Readiness Report 2019
March 16th, 2018
PM Readiness Report 2018 Summary
View all reports

Case Studies

View all case studies


June 25th, 2019
FLT3 testing in relapsed Acute Myeloid Leukemia setting is becoming increasingly common, but laboratory turnaround times (TAT) may be a barrier to treatment with second generation FLT3 inhibitors
The treatment landscape in AML has developed at an astonishing pace in the last 3 years, with 5 therapies being approved by the FDA. FLT3 inhibitors gilteritinib (Gil) and quizartinib (Quiz) present an unprecedented opportunity for improved surviv...
May 23rd, 2019
Diaceutics reviews the ongoing debate on diagnostics reform legislation
Thought leaders at Diaceutics recently authored a peer-reviewed article that covers the ongoing national debate over diagnostics reform legislation in the United States. The article is now available online ahead of print in the Journal of Molecula...
View all publications