From Blockbusters to Biomarkers: Rethinking Commercialization for the Precision Era and the Importance of Diagnostic Testing
Jordan Clark
It’s clear that traditional blockbuster models don't work well for precision medicine. Traditional models are built for broad patient groups. They can be costly and don’t fit the needs of therapies designed for specific biomarkers. Diagnostic testing helps identify the right patients for the right treatments.
Innovation Has Outpaced Commercialization.
Despite rapid advances in precision medicine, commercialization strategies have struggled to keep pace. The assumption that diagnostic testing will follow a drug launch has proven wrong. Testing can lag, and patients are missed if pharma, labs, diagnostics, and physicians don't collaborate early. Traditional models rely on large sales teams and broad campaigns. They often fail to reach physicians when treatment decisions are being made. Traditional models rely on large sales teams and broad campaigns. They often miss physicians at crucial moments when treatment decisions are made. The financial burden is immense and untenable for precision therapies.
As a result, we’re seeing promising treatments being deprioritized, abandoned, or returned to licensors. This is not due to clinical shortcomings, but because the commercial model cannot support their targeted nature.
The Case for Change.
This growing disconnect calls for a different approach, one as precise as the therapies it supports. Enter: Targeted Commercialization. Pioneered by Diaceutics to help new treatments reach the right patients at the right time.
What Makes Targeted Commercialization Different?
- Strategic Partnership, Not Just a Service. Targeted Commercialization starts with close collaboration and a clear understanding of each treatment.
- Powered by Real-World Data. This model uses real-time data to show what is happening across testing and treatment. Including where diagnostic testing gaps remain.
- Persona-Driven Engagement. We engage labs and physicians through digital and personal channels. Providing them with timely, relevant messages.
- Cost-Efficient, Flexible Models. Flexible pricing links costs to results, helping biopharma companies manage costs and reduce risk.
The Bottom Line
We believe commercialization should be as precise as the therapies it supports. And with Targeted Commercialization supported by diagnostic testing, we’re proving that it can be.
About Diaceutics
We’ve been with pharma and biotech companies for over 20 years, helping them to make more informed diagnostic and therapeutic decisions based on real-world data. Our platforms and tools provide global insight from a network of laboratories across 50+ countries.
This unparalleled visibility into real-world testing helps support therapy programs across oncology, cardiology, neurology, autoimmune, rare diseases, and many more.
Why don't traditional blockbuster commercialization models work for precision medicine?
Traditional blockbuster models are built for broad patient populations, relying on large sales teams and wide-reaching campaigns. Precision therapies target specific biomarkers and smaller patient groups, meaning these broad models are often too costly and fail to reach physicians at the exact moment treatment decisions are being made.
Why do precision medicines sometimes get deprioritized or abandoned despite strong clinical results?
Promising precision therapies are sometimes deprioritized, abandoned or returned to licensors, not because of clinical shortcomings, but because traditional commercial models can't financially or operationally support their targeted nature. This often happens when diagnostic testing lags behind drug launch and pharma, labs and physicians fail to collaborate early.
Why does diagnostic testing need to be aligned with drug launch timing?
Diagnostic testing is often assumed to naturally follow a drug launch, but in practice it can lag significantly, causing eligible patients to be missed. Early collaboration between pharma, diagnostic labs and physicians is essential to ensure testing infrastructure is ready to identify the right patients when a therapy becomes available.
What is Targeted Commercialization and how does it differ from traditional models?
Targeted Commercialization is an approach pioneered by Diaceutics that matches the precision of modern therapies with an equally precise commercial strategy. Rather than relying on broad sales campaigns, it uses real-world data, persona-driven engagement, and flexible pricing to connect new treatments with the right patients at the right time.
How does real-world data support precision medicine commercialization?
Real-world data reveals what is actually happening across testing and treatment in real time, including where diagnostic testing gaps remain. This allows commercial teams to identify where patients may be missed and respond with timely, targeted engagement rather than relying on assumptions about testing uptake.
What is persona-driven engagement in precision medicine commercialization?
Written By Jordan Clark
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